Precise dosing, fewer errors and maximum efficiency are crucial. We developed the OVD system to solve the problems of inefficient manual processes and high dosing errors, making the work of radiologists and pharmaceutical professionals safer and easier.
Why we had to act: Manual processes and their risks
Our extensive experience in automating complex processes always leads to the same conclusion: Manual processes are slow and carry a significant risk of errors. In radiopharmacy, these errors can have serious consequences – from incorrect dosages that compromise batch usability to severe threats to patient safety. On top of that, there’s immense regulatory pressure: precision, documentation, and compliance requirements are constantly increasing, and any deviation can lead to lengthy audits and high costs.
Radiology departments need to become more efficient, even with limited cleanroom space. The demand for compact, safe, and powerful systems is higher than ever. Yet, finding automated solutions that combine all these needs in one compact system is nearly impossible. This is exactly where the Open Vial Dispensing System (OVD) from the cts Group comes in.
We asked ourselves: How can we create a system that overcomes these obstacles and revolutionizes radiopharmacy? The result is the Open Vial Dispensing System (OVD) – a solution built from practice, for practice. Our vision was to create a standard product that not only addresses local but also global radiopharmacy challenges.
The journey: From idea to finished product
The development of the OVD system was anything but a straightforward success story – it was marked by setbacks, learning moments, and a relentless pursuit of perfection. We started with a stationary vial and a rotating tool magazine. This first version used pneumatic components, and we quickly hit the first obstacles: The pneumatic tools were too imprecise and lacked the flexibility needed to meet high standards.
After countless tests and failures, we decided to switch to electric tools. This decision was crucial – it allowed us to achieve the precision and flexibility required to meet the strict regulatory demands of radiopharmacy. It was a challenging process, but we knew it was the only way to deliver the quality that users need to produce safe products.
Another major challenge was the system’s housing. The entire system must operate reliably under high radiation, meaning all components must withstand this stress without losing functionality or stability. Our first attempts with a plastic housing failed due to a lack of stability. Robustness is essential, but at the same time, the system must not be too heavy. After numerous prototypes and materials, we settled on an anodized aluminum housing – stable, lightweight, and ideal for the requirements of a Class-A isolator.
AI and agility: How we found the optimal solution
A turning point in the development process was the challenge of creating a hygienic design that could reliably function under extreme radiation conditions and meet strict hygiene standards. This is where artificial intelligence came into play. We used AI to simulate different design approaches, especially those that ensured smooth, easy-to-clean surfaces, to find the optimal hygienic design before moving into the prototyping phase. By taking an agile approach, we identified potential issues early and iterated quickly. This saved time and allowed us to develop a well-thought-out, future-proof concept.
Constant iteration and learning from mistakes were key for us. Throughout the development process, we paused, reflected, and put the needs of our users first. Every decision – whether switching from pneumatic to electric tools or completely redesigning the housing – was based on real-world challenges. We needed to ensure that our system not only worked technically but also withstood the daily demands of the users. Every hurdle we overcame brought us closer to a product that meets market demands and genuinely improves the work of radiologists and pharmaceutical professionals.
The solution: A complete system that meets every requirement
The result is a complete system that meets the high demands of radiopharmacy. With a dosing accuracy of ± 1 µl and a self-calibrating weighing system, the OVD ensures each dose is filled precisely – without the risk of incorrect batches or technical errors. Additionally, the system automates complex recipe processes and ensures even the most demanding dosages are managed reliably and consistently. Designed to fit facilities with limited space, the compact system integrates seamlessly into existing cleanrooms and Class-A isolators.
Thanks to its hermetic process control, the OVD minimizes contamination risk while increasing user safety. Integrated quality assurance and an automated crimp function ensure a stable and scalable workflow, drastically reducing error sources. The OVD meets all key global standards, including cGMP, GAMP5, and FDA 21 CFR Part 11.
The result: A standard product for the future of radiopharmacy
The journey to this system was full of challenges – but every obstacle we faced made us stronger. Today, we are proud to have created a standard product that not only meets the daily needs of radiological departments but also addresses global challenges like the growing demand for personalized medicine.
With the OVD system, we deliver a strong solution that combines efficiency, precision, and safety. “The OVD system redefines radiopharmaceutical dosing,” says Alfred Pammer, VP of Sales, Marketing, and Product Management at cts. “We’re not just improving workflow – we’re setting a new standard for patient safety and operational excellence.”
Facing challenges in radiopharmacy like inefficient manual processes, high dosing errors, or limited space? Let’s solve these problems together with the OVD system. Contact our team – we’re here to help make your processes more efficient and ensure the safety of your operations.